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SMAC mimetic BV6 enables sensitization of resistant tumor cells but also affects cytokine-induced killer (CIK) cells: a potential challenge for combination therapy

Allogeneic hematopoietic stem cell transplantation (HSCT) is an established treatment option for high-risk hematological malignancies, and may also be offered to patients with solid malignancies refractory to conventional therapies. In case of patients’ relapse, refractory tumor cells may then be ta...

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Principais autores: Eva eRettinger, Andreas eGlatthaar, Behnaz eAhangarian Abhari, Sarah eOelsner, Verena ePfirrmann, Sabine eHuenecke, Selim eKuci, Hermann eKreyenberg, Andre M Willasch, Thomas eKlingebiel, Simone eFulda, Peter eBader
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014-07-01
coleção:Frontiers in Pediatrics
Assuntos:
Leukemia
tumors
cellular therapy
CIK cells
BV6
Acesso em linha:http://journal.frontiersin.org/Journal/10.3389/fped.2014.00075/full
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