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Dim light at night disrupts the sleep-wake cycle and exacerbates abnormal EEG activity in Cntnap2 knockout mice: implications for autism spectrum disorders

Abstract Background Epilepsy is a common comorbidity in individuals with autism spectrum disorders (ASDs). Many patients with epilepsy as well as ASD experience disruptions in their sleep-wake cycle and daily fluctuations in symptom severity. Chronic exposure to light at nighttime can disrupt sleep...

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Principais autores: Yumeng Wang, Ketema N. Paul, Gene D. Block, Tom Deboer, Christopher S. Colwell
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-12-01
Serier:Molecular Autism
Fag:
Autism spectrum disorder
Dim light at night
Epilepsy
Seizure
Mice
Sleep-wake rhythm
Online adgang:https://doi.org/10.1186/s13229-025-00689-7
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