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The role of the ADRB2 Thr164Ile variant in lung function determination, plasma proteome variability and other phenotypes in UK Biobank

Introduction The effect of coding polymorphisms of the β2-adrenergic receptor gene (ADRB2) on functional properties of the receptor is well established. We recently reported a genome-wide significant association between Thr164Ile and lung function, but the contribution of this variant to other trait...

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Библиографические подробности
Главные авторы: Katherine A. Fawcett, Robert J. Hall, Richard Packer, Kayesha Coley, Nick Shrine, Louise V. Wain, Martin D. Tobin, Ian P. Hall
Формат: Artigo
Язык:Inglês
Опубликовано: European Respiratory Society 2025-12-01
Серии:ERJ Open Research
Online-ссылка:https://doi.org/10.1183/23120541.00330-2025
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