Epigenetic regulation of NR5A2 influences colorectal cancer cell stemness via a stemness-related transcription factor NANOG

Abstract Objective Colorectal cancer (CRC) is an aggressive malignancy with high mortality, and the identification of upstream regulators of stemness represents a critical step toward developing more effective targeted therapies. This study aimed to define the role of NR5A2 in CRC, particularly in t...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Jia Liu, Li Li, Liang Zhang, Wenpeng Wang, Lei Zheng, Dalu Kong, Jiefu Wang, Yang Zhan
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2025-11-01
Цуврал:	Cell Communication and Signaling
Нөхцлүүд:	NR5A2 Colorectal cancer Cancer stem cell NANOG Epigenetic regulation
Онлайн хандалт:	https://doi.org/10.1186/s12964-025-02477-5
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!