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A computational method for cell type-specific expression quantitative trait loci mapping using bulk RNA-seq data

Abstract Mapping cell type-specific gene expression quantitative trait loci (ct-eQTLs) is a powerful way to investigate the genetic basis of complex traits. A popular method for ct-eQTL mapping is to assess the interaction between the genotype of a genetic locus and the abundance of a specific cell...

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Bibliografiske detaljer
Principais autores: Paul Little, Si Liu, Vasyl Zhabotynsky, Yun Li, Dan-Yu Lin, Wei Sun
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2023-05-01
Serier:Nature Communications
Online adgang:https://doi.org/10.1038/s41467-023-38795-w
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