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Mutanome Engineered RNA Immunotherapy: Towards Patient-Centered Tumor Vaccination

Advances in nucleic acid sequencing technologies have revolutionized the field of genomics, allowing the efficient targeting of mutated neoantigens for personalized cancer vaccination. Due to their absence during negative selection of T cells and their lack of expression in healthy tissue, tumor mut...

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Auteurs principaux: Mathias Vormehr, Barbara Schrörs, Sebastian Boegel, Martin Löwer, Özlem Türeci, Ugur Sahin
Format: Artigo
Langue:Inglês
Publié: Wiley 2015-01-01
Collection:Journal of Immunology Research
Accès en ligne:http://dx.doi.org/10.1155/2015/595363
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