Transcriptome and DNA Methylation Profiles of Mouse Fetus and Placenta Generated by Round Spermatid Injection

Low birth efficiency and developmental abnormalities in embryos derived using round spermatid injection (ROSI) limit the clinical application of this method. Further, the underlying molecular mechanisms remain elusive and warrant further in-depth study. In this study, the embryonic day (E) 11.5 mous...

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Hlavní autoři:	Haibo Zhu, Hao Sun, Dawei Yu, Tianda Li, Tang Hai, Chao Liu, Ying Zhang, Yurong Chen, Xiangpeng Dai, Ziyi Li, Wei Li, Ruizhi Liu, Guihai Feng, Qi Zhou
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2021-03-01
Edice:	Frontiers in Cell and Developmental Biology
Témata:	round spermatid injection transcriptome DNA methylation imprinted gene fetus placenta
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fcell.2021.632183/full
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