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Subsite-specific benefit of induction chemoimmunotherapy in HPV-negative oropharyngeal squamous cell carcinoma

PurposeTo evaluate whether the addition of immune checkpoint inhibitors (ICIs) to induction chemotherapy improves outcomes in HPV-negative oropharyngeal squamous cell carcinoma (OPSCC), and whether efficacy differs by primary tumor subsite.MethodsWe retrospectively analyzed 99 patients with newly di...

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Principais autores: Lin Zhu, Die Zhang, Jie Chen, Wei Qian, Peiyao Liu, Chunying Shen, Tingting Xu, Xin Zhou, Xueguan Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-06-01
coleção:Frontiers in Oncology
Assuntos:
definitive chemoradiotherapy
HPV-negative oropharyngeal squamous cell carcinoma
immune checkpoint inhibitors
induction chemotherapy
primary tumor subsite
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2026.1861897/full
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