Microtubules regulate migratory polarity through Rho/ROCK signaling in T cells.

<h4>Background</h4>Migrating leukocytes normally have a polarized morphology with an actin-rich lamellipodium at the front and a uropod at the rear. Microtubules (MTs) are required for persistent migration and chemotaxis, but how they affect cell polarity is not known.<h4>Methodology/principal findi...

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Detalhes bibliográficos

Principais autores:	Aya Takesono, Sarah J Heasman, Beata Wojciak-Stothard, Ritu Garg, Anne J Ridley
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2010-01-01
coleção:	PLoS ONE
Acesso em linha:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0008774&type=printable
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