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Overexpression of Heat Shock Protein 70 Improves Cardiac Remodeling and Survival in Protein Phosphatase 2A-Expressing Transgenic Mice with Chronic Heart Failure

Heat shock protein (HSP) 70 is a molecular chaperone that regulates protein structure in response to thermal stress. In addition, HSP70 is involved in post-translational modification and is related to the severity of some diseases. Here, we tested the functional relevance of long-lasting HSP70 expre...

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Main Authors: Somy Yoon, Ulrich Gergs, Julie R. McMullen, Gwang Hyeon Eom
Format: Artigo
Language:Inglês
Published: MDPI AG 2021-11-01
Series:Cells
Subjects:
post-translational modification
phosphorylation
dilated cardiomyopathy
heart failure
HSP70
Online Access:https://www.mdpi.com/2073-4409/10/11/3180
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