A Novel Iodine–Dextrin Complex Exhibits No Acute or Subacute Toxicity and Enhances Azithromycin Efficacy in an LPS-Induced Sepsis Model

<b>Background/Objectives:</b> Our work was designed to study the physicochemical properties, safety profile, pharmacokinetics, and prophylactic efficacy of an original iodine–dextrin-based pharmaceutical formulation (PA), both alone and in combination with azithromycin (AZ), in a murine model of LPS...

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Egile Nagusiak:	Nailya Ibragimova, Arailym Aitynova, Seitzhan Turganbay, Marina Lyu, Alexander Ilin, Karina Vassilyeva, Diana Issayeva, Tamari Gapurkhaeva, Arkadiy Krasnoshtanov, Galina Ponomareva, Amir Azembayev
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2025-08-01
Saila:	Pharmaceutics
Gaiak:	iodine–dextrin complex acute toxicity subacute toxicity pharmacokinetic study lipopolysaccharide sepsis
Sarrera elektronikoa:	https://www.mdpi.com/1999-4923/17/8/1040
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