3-Dimensional morphological characterization of neuroretinal microglia in Alzheimer’s disease via machine learning

Abstract Alzheimer’s Disease (AD) is a debilitating neurodegenerative disease that affects 47.5 million people worldwide. AD is characterised by the formation of plaques containing extracellular amyloid-β (Aβ) and neurofibrillary tangles composed of hyper-phosphorylated tau proteins (pTau). Aβ gradu...

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Bibliografiske detaljer

Principais autores:	Wissam B. Nassrallah, Hao Ran Li, Lyden Irani, Printha Wijesinghe, Peter William Hogg, Lucy Hui, Jean Oh, Ian R. Mackenzie, Veronica Hirsch-Reinshagen, Ging-Yuek Robin Hsiung, Wellington Pham, Sieun Lee, Joanne A. Matsubara
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2024-12-01
Serier:	Acta Neuropathologica Communications
Fag:	Alzheimer’s disease Neuroretinal microglia 3-Dimensional morphology Microglia morphology Microglia count Microglia size
Online adgang:	https://doi.org/10.1186/s40478-024-01898-6
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