GluA2 overexpression in oligodendrocyte progenitors promotes postinjury oligodendrocyte regeneration

Summary: Oligodendrocyte precursor cells (OPCs) are essential for developmental myelination and oligodendrocyte regeneration after CNS injury. These progenitors express calcium-permeable AMPA receptors (AMPARs) and form direct synapses with neurons throughout the CNS, but the roles of this signaling...

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Detalhes bibliográficos

Principais autores:	Rabia R. Khawaja, Amit Agarwal, Masahiro Fukaya, Hey-Kyeong Jeong, Scott Gross, Estibaliz Gonzalez-Fernandez, Jonathan Soboloff, Dwight E. Bergles, Shin H. Kang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2021-05-01
coleção:	Cell Reports
Assuntos:	oligodendrocyte OPC GluA2 remyelination AMPA receptor injury
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211124721004861
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