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Visualization of activity-regulated BDNF expression in the living mouse brain using non-invasive near-infrared bioluminescence imaging

Abstract Altered levels of brain-derived neurotrophic factor (BDNF) have been reported in neurologically diseased human brains. Therefore, it is important to understand how the expression of BDNF is controlled under pathophysiological as well as physiological conditions. Here, we report a method to...

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Principais autores: Mamoru Fukuchi, Ryohei Saito, Shojiro Maki, Nami Hagiwara, Yumena Nakajima, Satoru Mitazaki, Hironori Izumi, Hisashi Mori
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-09-01
Serier:Molecular Brain
Fag:
Bioluminescence
Brain-derived neurotrophic factor
In vivo imaging
Near-infrared
Online adgang:http://link.springer.com/article/10.1186/s13041-020-00665-7
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