Potential efficacy and preliminary mechanistic insights of the Jianpi Yishen Zhuanggu Tongluo formula for rheumatoid arthritis with sarcopenia-osteopenia: an integrated pilot study

ObjectivesTo explore the potential efficacy and identify preliminary metabolic biomarkers of the Jianpi Yishen Zhuanggu Tongluo formula (JPYSZGT) in rheumatoid arthritis (RA) complicated with sarcopenia-osteopenia (SO) using 1H-NMR-based metabolomics and in vitro experiments.MethodsIn this pilot stu...

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Autores principales:	Weidong Liang, Liuting Chen, Yadan Zhang, Jianhong Peng
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2026-04-01
Colección:	Frontiers in Pharmacology
Materias:	rheumatoid arthritis with sarcopenia-osteopenia Jianpi Yishen Zhuanggu Tongluo therapy pilot study metabolomics mitochondrion
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fphar.2026.1756789/full
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