Normal tissue radioprotection by amifostine via Warburg-type effects
Abstract The mechanism of Amifostine (WR-2721) mediated radioprotection is poorly understood. The effects of amifostine on human basal metabolism, mouse liver metabolism and on normal and tumor hepatic cells were studied. Indirect calorimetric canopy tests showed significant reductions in oxygen con...
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| Principais autores: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Portfolio
2016-08-01
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| Series: | Scientific Reports |
| Acceso en liña: | https://doi.org/10.1038/srep30986 |
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