Apoptosis signal-regulating kinase 1 mediates MPTP toxicity and regulates glial activation.

Apoptosis signal-regulating kinase 1 (ASK1), a member of the mitogen-activated protein kinase 3 family, is activated by oxidative stress. The death-signaling pathway mediated by ASK1 is inhibited by DJ-1, which is linked to recessively inherited Parkinson's disease (PD). Considering that DJ-1 defici...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Kang-Woo Lee, Xin Zhao, Joo-Young Im, Hilary Grosso, Won Hee Jang, Teresa W Chan, Patricia K Sonsalla, Dwight C German, Hidenori Ichijo, Eunsung Junn, M Maral Mouradian
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2012-01-01
coleção:	PLoS ONE
Acesso em linha:	http://europepmc.org/articles/PMC3254627?pdf=render
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!