The diagnostic significance of neurofilament heavy chains in cerebrospinal fluid in amyotrophic lateral sclerosis

Introduction. Early diagnosis of amyotrophic lateral sclerosis (ALS) is difficult because of the low sensitivity of clinical criteria at the early stages of the disease and the lack of reliable laboratory biomarkers. Neuron destruction leads to the release of excessively accumulated phosphorylated n...

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Autori principali:	Anastasia V. Vladykina, Vladimir D. Nazarov, Vladimir S. Krasnov, Ekaterina I. Koroleva, Polina A. Fedorova, Anna N. Moshnikova, Aleksandra V. Mazing, Sergey V. Lapin, Vladimir L. Emanuel, Dmitriy I. Rudenko, Fatima R. Stuchevskaya, Sergey M. Zatakovenko, Tatyana A. Pavlova, Tatyana M. Alekseeva, Vitaliy V. Goldobin
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Research Center of Neurology 2021-03-01
Serie:	Анналы клинической и экспериментальной неврологии
Soggetti:	amyotrophic lateral sclerosis neurofilaments neurofilament heavy chains biomarkers
Accesso online:	https://annaly-nevrologii.com/journal/pathID/article/viewFile/724/565
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