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Over-expression of TRESK K(+) channels reduces the excitability of trigeminal ganglion nociceptors.

TWIK-related spinal cord K(+) (TRESK) channel is abundantly expressed in trigeminal ganglion (TG) and dorsal root ganglion neurons and is one of the major background K(+) channels in primary afferent neurons. Mutations in TRESK channels are associated with familial and sporadic migraine. In rats, bo...

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Hlavní autoři: Zhaohua Guo, Yu-Qing Cao
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2014-01-01
Edice:PLoS ONE
On-line přístup:https://doi.org/10.1371/journal.pone.0087029
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