HIF1 inhibition targets tumoral and myeloid cells, and is a promising therapy for metastatic castration-resistant prostate cancer
Abstract Metastatic prostate cancer (PCa) remains lethal due to limited effective therapies. PTEN and TP53 are commonly mutated tumor suppressors in metastatic PCa, yet the molecular and cellular mechanisms driving aggressiveness and treatment resistance are not fully understood. We have previously...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2026-03-01
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| Serie: | Cell Death and Disease |
| Accesso online: | https://doi.org/10.1038/s41419-026-08590-8 |
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