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Establishment and evaluation of a PRRSV-sensitive porcine endometrial epithelial cell line by transfecting SV40 large T antigen

Abstract Background PRRSV is an infectious illness causing lung injury and abortion in sows. Cells apoptosis in the interface between the endometrium and fetal placenta is a crucial factor causing abortion. Previous study confirmed PRRSV could cause apoptosis of macrophages but rarely produced an ob...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Kang Zhang, Houshen Li, Shasha Dong, Ying Liu, Dong Wang, Haichang Liu, Feng Su, Lijiang Ge, Yunliang Jiang
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2019-08-01
Schriftenreihe:BMC Veterinary Research
Schlagworte:
Porcine endometrial epithelial cell line
SV40T antigen
PRRSV-sensitivity
Lentrival vector
Replication efficiency
Online-Zugang:http://link.springer.com/article/10.1186/s12917-019-2051-1
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