Evaluation of Drug Blood-Brain-Barrier Permeability Using a Microfluidic Chip

The blood-brain-barrier (BBB) is made up of blood vessels whose permeability enables the passage of some compounds. A predictive model of BBB permeability is important in the early stages of drug development. The predicted BBB permeabilities of drugs have been confirmed using a variety of in vitro m...

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Autores principales:	Jung Yoon Yang, Dae-Seop Shin, Moonkyu Jeong, Seong Soon Kim, Ha Neul Jeong, Byung Hoi Lee, Kyu-Seok Hwang, Yuji Son, Hyeon-Cheol Jeong, Chi-Hoon Choi, Kyeong-Ryoon Lee, Myung Ae Bae
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	MDPI AG 2024-04-01
Colección:	Pharmaceutics
Materias:	BBB microfluidic chip physiologically based pharmacokinetic modeling
Acceso en línea:	https://www.mdpi.com/1999-4923/16/5/574
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