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Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit

<p>Abstract</p> <p>background</p> <p>The pace of novel medical treatments and approaches to therapy has accelerated in recent years. Unfortunately, many potential therapeutic advances do not fulfil their promise when subjected to randomized controlled trials. It is therefore highly desirable to spee...

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Autori principali: Choodari-Oskooei Babak, Parmar Mahesh KB, Barthel Friederike M-S, Royston Patrick, Isham Valerie
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2011-03-01
Serie:Trials
Accesso online:http://www.trialsjournal.com/content/12/1/81
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