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Huangkui capsule mitigates diabetic nephropathy via epigenetic therapy effects

BackgroundHuangkui capsule (HKC), a Chinese herbal medicine derived from Abelmoschus manihot (L.) ethanol extract, has clinical efficacy against diabetic nephropathy (DN). Our research group has actively engaged in exploring the efficacy of HKC in treating DN. The underlying pharmacological mechanis...

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Autori principali: Yihong Yu, Haitao Tang, Nan Li, Haitao Ge, Jie Wu, Harvest F. Gu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2026-02-01
Serie:Frontiers in Pharmacology
Soggetti:
Abelmoschus manihot (L.)
diabetic nephropathy
DNA methylation
epigenetic pharmacology
transcriptome sequencing
whole genome bisulfite sequencing
Accesso online:https://www.frontiersin.org/articles/10.3389/fphar.2026.1775173/full
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