CLCA2 as a p53-Inducible Senescence Mediator
p53 is a tumor suppressor gene that is frequently mutated in multiple cancer tissues. Activated p53 protein regulates its downstream genes and subsequently inhibits malignant transformation by inducing cell cycle arrest, apoptosis, DNA repair, and senescence. However, genes involved in the p53-media...
Guardat en:
| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2012-02-01
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| Col·lecció: | Neoplasia: An International Journal for Oncology Research |
| Accés en línia: | http://www.sciencedirect.com/science/article/pii/S1476558612800431 |
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