Interleukin-1 beta promotes neuronal differentiation through the Wnt5a/RhoA/JNK pathway in cortical neural precursor cells

Abstract Pro-inflammatory cytokine interleukin-1 beta (IL-1β) is a key mediator of inflammation and stress in the central nervous system (CNS), and is highly expressed in the developing brain. In this study, we investigated the possible role of IL-1β in neuronal differentiation of cortical neural pr...

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Главные авторы:	Shin-Young Park, Min-Jeong Kang, Joong-Soo Han
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2018-07-01
Серии:	Molecular Brain
Предметы:	Interleukin-1 beta (IL-1β) Neuronal differentiation Wnt5a RhoA C-jun N-terminal kinase (JNK)
Online-ссылка:	http://link.springer.com/article/10.1186/s13041-018-0383-6
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