Antifibrotic Effect of the TGF-β Type I Receptor Inhibitor EW-7197 on Anastomotic Healing in a Rat Choledochojejunostomy Model

<b>Background/Aim</b>: Anastomotic stricture following choledochojejunostomy (CJS) is largely driven by fibrotic remodeling at the anastomotic site, a process mediated by transforming growth factor-β (TGF-β) signaling. This problem is particularly relevant in emergency biliary surgery, where CJS is...

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Κύριοι συγγραφείς:	Fırat Aslan, Serhat Binici, Iklil Eryılmaz, Burhan Beger, Orhan Beger, Ümit Haluk İliklerden, İbrahim Özalp, Zehra Akman İlik, Feyruz Karakoyun, Şahin Şahinalp, Muzaffer Önder Öner, Mehmet Çetin Kotan
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	MDPI AG 2026-03-01
Σειρά:	Biomedicines
Θέματα:	vactosertib EW-7197 biliary anastomosis fibrosis rat choledochojejunostomy
Διαθέσιμο Online:	https://www.mdpi.com/2227-9059/14/3/698
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