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Single-cell profiling of response to neoadjuvant chemo-immunotherapy in surgically resectable esophageal squamous cell carcinoma

Abstract Background The efficacy of neoadjuvant chemo-immunotherapy (NAT) in esophageal squamous cell carcinoma (ESCC) is challenged by the intricate interplay within the tumor microenvironment (TME). Unveiling the immune landscape of ESCC in the context of NAT could shed light on heterogeneity and...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Gang Ji, Qi Yang, Song Wang, Xiaolong Yan, Qiuxiang Ou, Li Gong, Jinbo Zhao, Yongan Zhou, Feng Tian, Jie Lei, Xiaorong Mu, Jian Wang, Tao Wang, Xiaoping Wang, Jianyong Sun, Jipeng Zhang, Chenghui Jia, Tao Jiang, Ming-gao Zhao, Qiang Lu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2024-04-01
Seri Bilgileri:Genome Medicine
Konular:
Esophageal squamous cell carcinoma
Neoadjuvant therapy
Single-cell sequencing
Pathological response
Online Erişim:https://doi.org/10.1186/s13073-024-01320-9
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