TGF-β1 overexpression in severe COVID-19 survivors and its implications for early-phase fibrotic abnormalities and long-term functional impairment

IntroductionIn post-COVID survivors, transforming growth factor-beta-1 (TGF-β1) might mediate fibroblast activation, resulting in persistent fibrosis.MethodsIn this study, 82 survivors of COVID-19-associated ARDS were examined at 6- and 24-months post-ICU discharge. At 6-months, quantitative CT anal...

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Hlavní autoři:	Enrique Alfaro, Raquel Casitas, Elena Díaz-García, Sara García-Tovar, Raúl Galera, María Torres-Vargas, María Fernández-Velilla, Cristina López-Fernández, José M. Añón, Manuel Quintana-Díaz, Francisco García-Río, Carolina Cubillos-Zapata
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-08-01
Edice:	Frontiers in Immunology
Témata:	post-COVID acute respiratory distress syndrome lung fibrosis transforming growth factor gas transfer components
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1401015/full
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