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Intranasal Delivery of Nerve Growth Factor in Neurodegenerative Diseases and Neurotrauma

Since the 1980s, the development of a pharmacology based on nerve growth factor (NGF) has been postulated for the therapy of Alzheimer’s disease (AD). This hypothesis was based on the rescuing effect of the neurotrophin on the cholinergic phenotype of the basal forebrain neurons, primarily compromis...

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Bibliografiske detaljer
Principais autores: Luigi Manni, Giorgio Conti, Antonio Chiaretti, Marzia Soligo
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021-11-01
Serier:Frontiers in Pharmacology
Fag:
Online adgang:https://www.frontiersin.org/articles/10.3389/fphar.2021.754502/full
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