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Microglia promote remyelination independent of their role in clearing myelin debris

Summary: Multiple sclerosis (MS) is an inflammatory disease characterized by myelin loss. While therapies exist to slow MS progression, no treatment currently exists for remyelination. Remyelination, linked to reduced disability in MS, relies on microglia and monocyte-derived macrophages (MDMs). Thi...

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Bibliografiske detaljer
Principais autores: Charbel S. Baaklini, Madelene F.S. Ho, Tristan Lange, Brady P. Hammond, Sharmistha P. Panda, Martin Zirngibl, Sameera Zia, Kassandre Himmelsbach, Heli Rana, Braxton Phillips, Daria Antoszko, Jeremies Ibanga, Mizuki Lopez, Kelly V. Lee, Michael B. Keough, Andrew V. Caprariello, Bradley J. Kerr, Jason R. Plemel
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2023-12-01
Serier:Cell Reports
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Online adgang:http://www.sciencedirect.com/science/article/pii/S2211124723015863
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