Upstrapping to determine futility: predicting future outcomes nonparametrically from past data

Abstract Background Clinical trials often involve some form of interim monitoring to determine futility before planned trial completion. While many options for interim monitoring exist (e.g., alpha-spending, conditional power), nonparametric based interim monitoring methods are also needed to accoun...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Jessica L. Wild, Adit A. Ginde, Christopher J. Lindsell, Alexander M. Kaizer
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	BMC 2024-05-01
Sarja:	Trials
Aiheet:	Interim monitoring Futility monitoring Upstrap Nonparametric Alpha-spending Conditional power
Linkit:	https://doi.org/10.1186/s13063-024-08136-3
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