Lipoxins reduce obesity-induced adipose tissue inflammation in 3D-cultured human adipocytes and explant cultures

Summary: Adipose tissue inflammation drives obesity-related cardiometabolic diseases. Enhancing endogenous resolution mechanisms through administration of lipoxin A4, a specialized pro-resolving lipid mediator, was shown to reduce adipose inflammation and subsequently protects against obesity-induce...

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Huvudupphov:	Matúš Soták, Meenu Rohini Rajan, Madison Clark, Matthew Harms, Alankrita Rani, Jamie D. Kraft, David Tandio, Tong Shen, Kamil Borkowski, Oliver Fiehn, John W. Newman, Marianne Quiding-Järbrink, Christina Biörserud, Peter Apelgren, Trude Staalesen, Carolina E. Hagberg, Jeremie Boucher, Ville Wallenius, Stephan Lange, Emma Börgeson
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Elsevier 2022-07-01
Serie:	iScience
Ämnen:	Precision medicine Biological sciences Physiology Human metabolism Cell biology
Länkar:	http://www.sciencedirect.com/science/article/pii/S2589004222008744
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