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Modelling metastatic colonization of cholangiocarcinoma organoids in decellularized lung and lymph nodes

Cholangiocarcinoma (CCA) is a type of liver cancer with an aggressive phenotype and dismal outcome in patients. The metastasis of CCA cancer cells to distant organs, commonly lung and lymph nodes, drastically reduces overall survival. However, mechanistic insight how CCA invades these metastatic sit...

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Detalles Bibliográficos
Principais autores: Gilles S. van Tienderen, Marije E. A. van Beek, Ivo J. Schurink, Oskar Rosmark, Henk P. Roest, Jantine Tieleman, Jeroen Demmers, Iain Muntz, James Conboy, Gunilla Westergren-Thorsson, Gijsje Koenderink, Luc JW van der Laan, Monique M. A. Verstegen
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Oncology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fonc.2022.1101901/full
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