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sEV-mediated lipid droplets transferred from bone marrow adipocytes promote ferroptosis and impair osteoblast function

Osteoporosis is linked to increased bone marrow adipocyte (BMAd) proliferation, which displaces bone-forming cells and alters the local environment. The impact of BMAd lipid droplets on bone health and osteoblast function remains unclear. This study investigates the interplay between BMAd-derived li...

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Autors principals: Weibo Huang, Feng Hua, Tong Su, Chenghao Zhou, Kangcheng Zhao, Dianwen Song
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2024-11-01
Col·lecció:Journal of Lipid Research
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Accés en línia:http://www.sciencedirect.com/science/article/pii/S0022227524001627
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