microRNA-17-5p downregulation inhibits autophagy and myocardial remodelling after myocardial infarction by targeting STAT3

MicroRNAs (miRs) are reported to regulate myocardial infarction (MI). This study was performed to investigate the function and mechanism of miR-17-5p in myocardial remodelling after MI. Initially, a mouse model of MI was established and MI mice were infected with lentivirus antago-miR-17-5p vector....

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Auteurs principaux:	Bo Chen, Yingjun Yang, Jinbo Wu, Jianjiang Song, Jia Lu
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis Group 2022-01-01
Collection:	Autoimmunity
Sujets:	myocardial infarction myocardial remodelling microrna-17-5p stat3 autophagy myocardial fibrosis cardiomyocyte apoptosis
Accès en ligne:	http://dx.doi.org/10.1080/08916934.2021.1992754
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