Hepatitis C virus exploits cyclophilin A to evade PKR

Counteracting innate immunity is essential for successful viral replication. Host cyclophilins (Cyps) have been implicated in viral evasion of host antiviral responses, although the mechanisms are still unclear. Here, we show that hepatitis C virus (HCV) co-opts the host protein CypA to aid evasion...

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Principais autores:	Che C Colpitts, Sophie Ridewood, Bethany Schneiderman, Justin Warne, Keisuke Tabata, Caitlin F Ng, Ralf Bartenschlager, David L Selwood, Greg J Towers
格式:	Artigo
語言:	Inglês
出版:	eLife Sciences Publications Ltd 2020-06-01
叢編:	eLife
主題:	virus-host interactions innate antiviral immunity viral evasion hepatitis C virus cyclophilin A protein kinase R
在線閱讀:	https://elifesciences.org/articles/52237
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