Cortical hierarchy and aphasia severity: the sensorimotor–association gradient modulates lesion effects within language-specific networks

Abstract Aphasia severity after stroke varies widely and is not fully explained by lesion size or location. We propose that incorporating the brain’s sensorimotor-association (S-A) gradient, reflecting cortical hierarchy, offers a biologically grounded framework for predicting language outcomes. In...

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Bibliografische Detailangaben

Hauptverfasser:	Ida Rangus, Natalie Busby, Nicholas Riccardi, Sigfus Kristinsson, Janina Wilmskoetter, Dirk B. den Ouden, Chris Rorden, Roger Newman-Norlund, Julius Fridriksson, Leonardo Bonilha
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2026-01-01
Schriftenreihe:	Communications Biology
Online-Zugang:	https://doi.org/10.1038/s42003-025-09375-z
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