Parallel Murine and Human Aortic Wall Genomics Reveals Metabolic Reprogramming as Key Driver of Abdominal Aortic Aneurysm Progression

Background While numerous interventions effectively interfered with abdominal aortic aneurysm (AAA) formation/progression in preclinical models, none of the successes translated into clinical success. Hence, a systematic exploration of parallel and divergent processes in clinical AAA disease and its...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Gabor Gäbel, Bernd H. Northoff, Amanda Balboa, Mediha Becirovic‐ Agic, Marcelo Petri, Albert Busch, Lars Maegdefessel, Adrian Mahlmann, Stefan Ludwig, Daniel Teupser, Vivian de Waard, Jonathan Golledge, Anders Wanhainen, Dick Wågsäter, Lesca M. Holdt, Jan H. N. Lindeman
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2021-09-01
coleção:	Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Assuntos:	abdominal aortic aneurysm angiotensin II model elastase model gene expression glycolysis human
Acesso em linha:	https://www.ahajournals.org/doi/10.1161/JAHA.120.020231
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!