Enhancing radiation-induced reactive oxygen species generation through mitochondrial transplantation in human glioblastoma

Abstract Glioblastoma (GBM) is the most aggressive primary brain malignancy in adults, with high recurrence rates and resistance to standard therapies. This study explores mitochondrial transplantation as a novel method to enhance the radiobiological effect (RBE) of ionizing radiation (IR) by increa...

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Egile Nagusiak:	Kent L. Marshall, Murugesan Velayutham, Valery V. Khramtsov, Alan Mizener, Christopher P. Cifarelli
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Nature Portfolio 2025-03-01
Saila:	Scientific Reports
Gaiak:	Glioblastoma Mitochondria ROS EPR Radiation Cell-penetrating peptide
Sarrera elektronikoa:	https://doi.org/10.1038/s41598-025-91331-2
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