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Direct detection of Gram-negative bacilli and extended-spectrum β-lactamase producers in positive blood culture specimens using MALDI-TOF MS

Bloodstream infections caused by antimicrobial-resistant Gram-negative bacilli are often difficult to treat. Here, we investigated the performance of a workflow for direct detection of Gram-negative bacilli and extended-spectrum β-lactamase (ESBL) producers in positive blood culture (PBC) specimens...

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Principais autores: Kosuke Kosai, Yasuhide Kawamoto, Fujiko Mitsumoto-Kaseida, Norihito Kaku, Hiroo Hasegawa, Takahiro Takazono, Koichi Izumikawa, Hiroshi Mukae, Katsunori Yanagihara
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2025-11-01
coleção:Frontiers in Cellular and Infection Microbiology
Assuntos:
bloodstream infection
antimicrobial resistance
β-lactamase
rapid detection
workflow
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1701423/full
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