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Germline Missense Changes in the APC Gene and Their Relationship to Disease

<p>Abstract</p> <p>Familial adenomatous polyposis (FAP) is characterized by the presence of hundreds to thousands of adenomas that carpet the entire colon and rectum. Nonsense and frameshift mutations in the adenomatous polyposis coli (APC) gene account for the majority of mutations identified to da...

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Váldodahkkit: Scott Rodney J, Crooks Renee, Rose Lindy, Attia John, Thakkinstian Ammarin, Thomas Lesley, Spigelman Allan D, Meldrum Cliff J
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2004-05-01
Ráidu:Hereditary Cancer in Clinical Practice
Fáttát:
Liŋkkat:http://www.hccpjournal.com/content/2/2/81
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