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Melatonin treatment of pigs with acute pancreatitis reduces inflammatory reaction of pancreatic tissue and enhances fitness score of pigs: experimental research

Abstract Background Severe acute pancreatitis is associated with high morbidity and mortality. Melatonin is known as the activator of antioxidant enzymes. The main purpose of this study was to evaluate the clinical effect of melatonin treatment in a pig model with induced acute pancreatitis. Methods...

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Principais autores: Katharina Grupp, Johannes Erbes, Annika Poppe, Karin Wodack, Andreas Gocht, Constantin Trepte, Jan Havel, Oliver Mann, Jakob R. Izbicki, Kai Bachmann
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-04-01
Serier:World Journal of Emergency Surgery
Fag:
Acute pancreatitis
Experimental model
Melatonin
Inflammation
Edema
Fitness score
Online adgang:http://link.springer.com/article/10.1186/s13017-019-0237-2
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