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Isoforsythiaside confers neuroprotection against Alzheimer’s disease by attenuating ferroptosis and neuroinflammation in vivo and in vitro

Ferroptosis and neuroinflammation contribute to the development of Alzheimer's disease (AD). Isoforsythiaside (IFY) is a phenylethanoid glycoside isolated from the dried fruit of Forsythia suspensa (Thunb.) Vahl that has been confirmed to improve the memory and cognitive abilities of APP/PS1 mice in...

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Main Authors: Chunyue Wang, Hongbo Jiang, Honghan Liu, Shanshan Chen, Hangyu Guo, Shuoshuo Ma, Weiwei Han, Yu Li, Di Wang
Format: Artigo
Language:Inglês
Published: Tsinghua University Press 2023-09-01
Series:Food Science and Human Wellness
Subjects:
Ferroptosis
Neuroinflammation
Isoforsythiaside
Alzheimer's disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2213453023000356
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