A longitudinal epigenome-wide association study of preeclamptic and normotensive pregnancy

Abstract Background While preeclampsia (PE) is a leading cause of pregnancy-related morbidity/mortality, its underlying mechanisms are not fully understood. DNA methylation (DNAm) is a dynamic regulator of gene expression that may offer insight into PE pathophysiology and/or serve as a biomarker (e....

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Autori principali:	Shuwei Liu, Haoyi Fu, Mitali Ray, Lacey W. Heinsberg, Yvette P. Conley, Cindy M. Anderson, Carl A. Hubel, James M. Roberts, Arun Jeyabalan, Daniel E. Weeks, Mandy J. Schmella
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2023-01-01
Serie:	Epigenetics Communications
Soggetti:	Preeclampsia Pre-eclampsia DNA methylation Epigenetics Hypertensive disorder of pregnancy Surrogate variable analysis
Accesso online:	https://doi.org/10.1186/s43682-022-00014-w
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