Hydroxyhexylitaconic acids as potent IMP-type metallo-β-lactamase inhibitors for controlling carbapenem resistance in Enterobacterales

ABSTRACTMetallo-β-lactamases (MBLs) represent one of the main causes of carbapenem resistance in the order Enterobacterales. To combat MBL-producing carbapenem-resistant Enterobacterales, the development of MBL inhibitors can restore carbapenem efficacy for such resistant bacteria. Microbial natural...

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ग्रंथसूची विवरण

मुख्य लेखकों:	Jun-ichi Wachino, Wanchun Jin, Chihiro Norizuki, Kouji Kimura, Motonori Tsuji, Hiromasa Kurosaki, Yoshichika Arakawa
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	American Society for Microbiology 2024-03-01
श्रृंखला:	Microbiology Spectrum
विषय:	metallo-β-lactamase Enterobacterales inhibitors
ऑनलाइन पहुंच:	https://journals.asm.org/doi/10.1128/spectrum.02344-23
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