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Detection and classification of chromosomes with sister chromatid cohesion defects using object detection models

Abstract Sister chromatid cohesion (SCC) is mediated by a protein complex called cohesin and by regulatory proteins that control cohesin function. A commonly used approach to evaluate the involvement of cohesin regulatory proteins is to classify the shape of the chromosomes after depletion of the ta...

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Principais autores: Shinya Matsumoto, Miku Sojo, Kosuke Oshima, Kiyoshi Nishikawa, Kan Okubo, Takuya Abe
Format: Artigo
Jezik:Inglês
Izdano: Nature Portfolio 2026-03-01
Serija:Scientific Reports
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Online dostop:https://doi.org/10.1038/s41598-026-43009-6
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