Modulating tumor-associated macrophage polarization by anti-maRCO mAb exerts anti-osteosarcoma effects through regulating osteosarcoma cell proliferation, migration and apoptosis

Abstract Purpose Osteosarcoma is a primary bone tumor lacking optimal clinical treatment options. Tumor-associated macrophages in the tumor microenvironment are closely associated with tumor development and metastasis. Studies have identified the macrophage receptor with collagenous structure (MARCO...

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Autores principales:	Lei Ding, Ling Wu, Yuting Cao, Hao Wang, Defang Li, Weibin Chen, Ping Huang, Zengxin Jiang
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	BMC 2024-07-01
Colección:	Journal of Orthopaedic Surgery and Research
Materias:	Macrophage MARCO Osteosarcoma Co-culture Polarization
Acceso en línea:	https://doi.org/10.1186/s13018-024-04950-2
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