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Differential expression of components of the CGRP-receptor family in human coronary and human middle meningeal arteries: functional implications

Abstract Background Different responses in human coronary arteries (HCA) and human middle meningeal arteries (HMMA) were observed for some of the novel CGRP receptor antagonists, the gepants, for inhibiting CGRP-induced relaxation. These differences could be explained by the presence of different re...

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Principais autores: Tessa de Vries, Dennis Schutter, Antoon van den Bogaerdt, Arnaud Vincent, Ruben Dammers, A. H. Jan Danser, Antoinette MaassenVanDenBrink
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-10-01
coleção:The Journal of Headache and Pain
Assuntos:
Adrenomedullin
AM22-52
CGRP
Human arteries
Olcegepant
qPCR
Acesso em linha:https://doi.org/10.1186/s10194-024-01863-7
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