Understanding PI3K/Akt/mTOR signaling in squamous cell carcinoma: mutated PIK3CA as an example

Abstract Compared with those in adenocarcinoma, PIK3CA mutations are more common in squamous cell carcinoma (SCC), which arises from stratified squamous epithelia that are usually exposed to adverse environmental factors. Although hotspot mutations in exons 9 and 20 of PIK3CA, including E542K, E545K...

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Xehetasun bibliografikoak

Egile Nagusiak:	Shutao Zheng, Shuo He, Yan Liang, Yiyi Tan, Qing Liu, Tao Liu, Xiaomei Lu
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Springer 2024-04-01
Saila:	Molecular Biomedicine
Gaiak:	PI3K PIK3CA Mutation Squamous cell carcinoma Resistance
Sarrera elektronikoa:	https://doi.org/10.1186/s43556-024-00176-0
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